6,526 research outputs found

    Some Factors Involved in the Manufacture of Brick Cheese

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    The flavor, quality and composition of market brick cheese varies greatly. Its moisture content often ranges from 37 to 43 per cent. The flavor may be similar to Limburger or it may even resemble that of Cheddar. Such a great variation in a specific food product tends toward disappointment for the consumer. It is believed that a more uniform standard of quality for this product is needed to materially increase its consumption. Therefore, a detailed study of some of the factors involved in the manufacture of brick cheese may help to improve the quality and aid in determining a satisfactory standard

    Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase

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    Chk1 protein kinase maintains replication fork stability in metazoan cells in response to DNA damage and DNA replication inhibitors. Here, we have employed DNA fiber labeling to quantify, for the first time, the extent to which Chk1 maintains global replication fork rates during normal vertebrate S phase. We report that replication fork rates in Chk1¿/¿ chicken DT40 cells are on average half of those observed with wild-type cells. Similar results were observed if Chk1 was inhibited or depleted in wild-type DT40 cells or HeLa cells by incubation with Chk1 inhibitor or small interfering RNA. In addition, reduced rates of fork extension were observed with permeabilized Chk1¿/¿ cells in vitro. The requirement for Chk1 for high fork rates during normal S phase was not to suppress promiscuous homologous recombination at replication forks, because inhibition of Chk1 similarly slowed fork progression in XRCC3¿/¿ DT40 cells. Rather, we observed an increased number of replication fibers in Chk1¿/¿ cells in which the nascent strand is single-stranded, supporting the idea that slow global fork rates in unperturbed Chk1¿/¿ cells are associated with the accumulation of aberrant replication fork structure

    The Handbook of Clinic Practice

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    The Handbook of Clinic Practice is a major surviving document that shows Dr. Kelly\u27s early development as a clinician. The Handbook began as a guide for bachelor and master level students working in the Clinc. This was a major teaching tool for Dr. Kelly during his years at Fort Hays Kansas State College. It represents his early position regarding behavior in a clinical setting, and also provides a glimpse of the immense variety and scope of Dr. Kelly\u27s talents.https://scholars.fhsu.edu/fort_hays_studies_series/1048/thumbnail.jp

    Rapid formation of large aggregates during the spring bloom of Kerguelen Island: observations and model comparisons

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    International audienceWhile production of aggregates and their subsequent sinking is known to be one pathway for the downward movement of organic matter from the euphotic zone, the rapid transition from non-aggregated to aggregated particles has not been reported previously. We made one vertical profile of particle size distributions (PSD; sizes ranging from 0.052 to several millimeters in equivalent spherical diameter) at pre-bloom stage and seven vertical profiles 3 weeks later over a 48 h period at early bloom stage using the Underwater Vision Profiler during the Kerguelen Ocean and Plateau Compared Study cruise 2 (KEOPS2, October– November 2011). In these naturally iron-fertilized waters southeast of Kerguelen Island (Southern Ocean), the total particle numerical abundance increased by more than four-fold within this time period. A massive total volume increase associated with particle size distribution changes was observed over the 48 h survey, showing the rapid formation of large particles and their accumulation at the base of the mixed layer. The results of a one-dimensional particle dynamics model support coagulation as the mechanism responsible for the rapid aggregate formation and the development of the V T subsurface maxima. The comparison of V T profiles between early bloom stage and pre-bloom stage indicates an increase of particulate export below 200 m when bloom has developed. These results highlight the role of coagulation in forming large particles and triggering carbon export at the early stage of a naturally iron-fertilized bloom, while zoo-plankton grazing may dominate later in the season. The rapid changes observed illustrate the critical need to measure carbon export flux with high sampling temporal resolution. Our results are the first published in situ observations of the rapid accumulation of marine aggregates and their export and the general agreement of this rapid event with a model of phyto-plankton growth and coagulation

    Bremsstrahlung in Alpha-Decay

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    We present the first fully quantum mechanical calculation of photon radiation accompanying charged particle decay from a barrier resonance. The soft-photon limit agrees with the classical results, but differences appear at next-to-leading-order. Under the conditions of alpha-decay of heavy nuclei, the main contribution to the photon emission stems from Coulomb acceleration and may be computed analytically. We find only a small contribution from the tunneling wave function under the barrier.Comment: 12 pages, 2 Postscript figure

    Fundamental Behavior of Electric Field Enhancements in the Gaps Between Closely Spaced Nanostructures

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    We demonstrate that the electric field enhancement that occurs in a gap between two closely spaced nanostructures, such as metallic nanoparticles, is the result of a transverse electromagnetic waveguide mode. We derive an explicit semianalytic equation for the enhancement as a function of gap size, which we show has a universal qualitative behavior in that it applies irrespective of the material or geometry of the nanostructures and even in the presence of surface plasmons. Examples of perfect electrically conducting and Ag thin-wire antennas and a dimer of Ag spheres are presented and discussed.Comment: 9 pages and 4 figure

    Ohm's Law for a Relativistic Pair Plasma

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    We derive the fully relativistic Ohm's law for an electron-positron plasma. The absence of non-resistive terms in Ohm's law and the natural substitution of the 4-velocity for the velocity flux in the relativistic bulk plasma equations do not require the field gradient length scale to be much larger than the lepton inertial lengths, or the existence of a frame in which the distribution functions are isotropic.Comment: 12 pages, plain TeX, Phys. Rev. Lett. 71 3481 (1993

    Phase equilibria and critical behavior of square‐well fluids of variable width by Gibbs ensemble Monte Carlo simulation

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    The vapor–liquid phase equilibria of square†well systems with hard†sphere diameters σ, well†depths ε, and ranges λ=1.25, 1.375, 1.5, 1.75, and 2 are determined by Monte Carlo simulation. The two bulk phases in coexistence are simulated simultaneously using the Gibbs ensemble technique. Vapor–liquid coexistence curves are obtained for a series of reduced temperatures between about Tr=T/Tc=0.8 and 1, where Tc is the critical temperature. The radial pair distribution functions g(r) of the two phases are calculated during the simulation, and the results extrapolated to give the appropriate contact values g(σ), g(λσ−), and g(λσ+). These are used to calculate the vapor†pressure curves of each system and to test for equality of pressure in the coexisting vapor and liquid phases. The critical points of the square†well fluids are determined by analyzing the density†temperature coexistence data using the first term of a Wegner expansion. The dependence of the reduced critical temperature T* c=kTc/ε, pressure P* c=Pcσ3/ε, number density Ï * c=Ï cσ3, and compressibility factor Z=P/(Ï kT), on the potential range λ, is established. These results are compared with existing data obtained from perturbation theories. The shapes of the coexistence curves and the approach to criticality are described in terms of an apparent critical exponent β. The curves for the square†well systems with λ=1.25, 1.375, 1.5, and 1.75 are very nearly cubic in shape corresponding to near†universal values of β (β≊0.325). This is not the case for the system with a longer potential range; when λ=2, the coexistence curve is closer to quadratic in shape with a near†classical value of β (β≊0.5). These results seem to confirm the view that the departure of β from a mean†field or classical value for temperatures well below critical is unrelated to long†range, near†critical fluctuations

    The ASCA X-Ray Spectrum Of The Broad-Line Radio Galaxy Pictor A: A Simple Power Law With No Fe K-alpha Line

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    We present the X-ray spectrum of the broad-line radio galaxy Pictor A as observed by ASCA in 1996. The main objective of the observation was to detect and study the profiles of the Fe~Kα\alpha lines. The motivation was the fact that the Balmer lines of this object show well-separated displaced peaks, suggesting an origin in an accretion disk. The 0.5-10 keV X-ray spectrum is described very well by a model consisting of a power law of photon index 1.77 modified by interstellar photoelectric absorption. We find evidence for neither a soft nor a hard (Compton reflection) excess. More importantly, we do not detect an Fe K-alpha line, in marked contrast with the spectra of typical Seyfert galaxies and other broad-line radio galaxies observed by ASCA. The 99%-confidence upper limit on the equivalent width of an unresolved line at a rest energy of 6.4 keV is 100 eV, while for a broad line (FWHM of approximately 60,000 km/s) the corresponding upper limit is 135 eV. We discuss several possible explanations for the weakness of the Fe K-alpha line in Pictor~A paying attention to the currently available data on the properties of Fe K-alpha lines in other broad-line radio galaxies observed by ASCA. We speculate that the absence of a hard excess (Compton reflection) or an Fe K-alpha line is an indication of an accretion disk structure that is different from that of typical Seyfert galaxies, e.g., the inner disk may be an ion torus.Comment: To appear in the Astrophysical Journal (18 pages, including 8 postscript figures; uses psfig.tex
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